The List, a CEA Tech institute, carries out research on smart digital systems. Its R&D programs, all with potentially major economic and social implications, focus on advanced manufacturing, cyberphysical systems, artificial intelligence and digital health. By developing cutting-edge technological research with applications in various industrial markets (transport, defense and security, manufacturing, energy…), the List helps its industrial partners to enhance their competitiveness through innovation and technology transfer. The List covers each development aspect of software for AI, Industry 4.0 and embedded systems, offering methods, tools and components that will optimize systems quality (including safety, security, reliability) and performance. Architecture, hardware and software aspects are integrated into the global performance system service no matter the complexity: multifunction systems, critical systems, big data management etc.